Hi there ~
I understand your concern and it is hard to treat macular amyloidosis, as you mention that you have tried many treatments in the past. Because of the growing appreciation of the importance of pruritus
as the primary trigger for the deposition of amyloid, treatment modalities are directed toward the relief of pruritus in macular amyloidosis. Sedating antihistamines have been found to be moderately effective. Topical dimethyl sulfoxide (DMSO), a chemical solvent, and intralesional steroids
are beneficial if combined with other modalities. DMSO has been used with moderate success, but failures have also been reported. However there is little evidence that DMSO is helpful in cutaneous amyloidosis
. Treatment with ultraviolet B (UV-B) light can provide symptomatic relief. The use of pulsed dye laser therapy
, for both pruritus and the papular eruption of lichen amyloidosis with significant improvement has been noted. Transcutaneous electrical nerve stimulation may also be helpful. I recommend that you consult a good dermatologist
for the approved therapies in your area with the above information.
I hope this helps. Take care and have a lovely day!