Welcome to HCM. I have gone through your question and understand your concerns.
These medications are mostly safe without much side effects. Common side effects seen in practice are:Thyronorm
Orlistat : Gastritis, abdominal discomfort, passing fat in stools
Metaforte: Gastritis, diarrhoea
Hope I have answered your query. If you have any further questions I will be happy to help
With warm regards,
Dr Ajish TP (MD,DM)