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Side effects of taking Isoniazid on liver? Alternative?

I have been taking Isoniazid 300mg 1x day (this is the first month of of a nine month treatment) and am concerned about the med s effect on my liver ( toxicity ). 1)Is there anything that can reduce the toxic side effect? 2) Would fiber psylium supplement be beneficial or not a good idea to help rid the body of waste (acetylisoniazid)?
Asked On : Mon, 30 Jul 2012
Answers:  1 Views:  139
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Endocrinologist 's  Response
The question is why are you taking Isoniazid ? Is it for prophylaxis or is it part of tuberculosis regimen ? Yes Isoniazid has liver toxicity but not in all patients .. Only some patients develop raised liver enzymes because of isoniazid. Do have an underlying liver disease ? If not there is nothing to worry. Go for a baselne Liver function test and repeat it after three months , if the ALT and AST has not increased by > 3 times the upper limit of normal then there is nothing to worry. You dont need to take any other medications to prevent liver toxicity.
Answered: Tue, 31 Jul 2012
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