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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Shrunken Testicle, Sensitive, Low Ejaculate. Have High PSA With Negative Biopsy. Common?

My right testicle seems to have shrunk to almost non existence.. Has been very sensitive in the past. Low ejaculate. Ejaculation very very seldom.. 68 year old man. Have had high psa for many years with negative biopsy . Skeptical of the benefit of further biopsy. Is this common??? Of concern?? What are the appropriate questions?
Sat, 30 Mar 2013
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General & Family Physician,  's  Response
Hello,
Thanks for your query.
In old age men usually have shrunken testes, it is not a thing to be worried about. The problem that needs to be addressed is your raised PSA levels. Usually it suggests prostatic cancer with help of other physical findings. There are many other conditions which may show raised PSA like Benign Prostatic Hyperplasia,Prostatitis (inflamed prostrate) etc
Negative biopsies do not always rule out prostate cancer and further biopsies may be needed if your PSA remains raised or increases with time. you may need further blood test to measure the free/total PSA ratio (FTR).
Visit your concerned doctor, reevaluate PSA levels and biopsies and rule out other conditions.
Note: avoid any sexual activity for at least a couple of days before your PSA blood test, as it may raise PSA levels.

Hope it helps.
Take Care!
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Shrunken Testicle, Sensitive, Low Ejaculate. Have High PSA With Negative Biopsy. Common?

Hello, Thanks for your query. In old age men usually have shrunken testes, it is not a thing to be worried about. The problem that needs to be addressed is your raised PSA levels. Usually it suggests prostatic cancer with help of other physical findings. There are many other conditions which may show raised PSA like Benign Prostatic Hyperplasia,Prostatitis (inflamed prostrate) etc Negative biopsies do not always rule out prostate cancer and further biopsies may be needed if your PSA remains raised or increases with time. you may need further blood test to measure the free/total PSA ratio (FTR). Visit your concerned doctor, reevaluate PSA levels and biopsies and rule out other conditions. Note: avoid any sexual activity for at least a couple of days before your PSA blood test, as it may raise PSA levels. Hope it helps. Take Care!