My husband was dx'd with Stage IVB Hodgkins 9-09. He has had 2 chemo regimes (his disease became refractory after both courses) and an autologous SCT preceded by high dose chemo in Sept. of last year. He had a (-) PET scan in Nov. Unfortunately he has now relapsed with mets to the liver. His hem/onc has recommended a mismatched allogeneic SCT using his sister's cells which is a 50% match to his. Do you think this is a reasonable course? Also could you tell me what end stage Hodgkins with liver involvement would be like if he fails to obtain remission if he proceeds with the transplant. Thank you in advance.