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Severe migraines going worse. MRI in the past showed focal nonspecific gloss. Meaning?

my son started having migranes a few years ago, lately they have been getting worse, we tried a few different medicines but non worked, he got a mri a year ago and they told me it was bad migranes, since they are getting worse i am going back to the neorologist and i pulled out the old results and it says punctate focus of high signal seen in the subcortical white matter in the right frontal lobe , nospecific. this could be due to chronic migraine disorder or represent focal nonspecific gliosis . the rest of the brain is normal.....what does focal nonspecific gliosis mean.....
Asked On : Sat, 22 Dec 2012
Answers:  1 Views:  59
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Neurologist 's  Response
Nov 2013
Thank you for posting your query.

MRI findings of focal non-specific gliosis means small areas of decreased blood flow, which mainly occurs in front of brain. This is common in people with chronic migraines.

This findings could also occur in mini brain strokes and demyelinating illness such as multiple sclerosis. However, I also agree that in your son's case, these findings are due to migraine.

If medications have not helped your son, he could go for botox injection therapy.
I hope it helps. Please get back if you require any additional information.

Wishing you good health,

Dr Sudhir Kumar MD (Internal Medicine), DM (Neurology)
Senior Consultant Neurologist
Apollo Hospitals, Hyderabad, India
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Answered: Sun, 17 Nov 2013
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