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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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SGPT level 91, bilirubin 0.25, What are the causes of the increase of this parameters?

Hi, My SGPT level is increased to 91 and bilirubin has increased to 0.25, What are the causes of the increase of this parameters, I drink alcohol once in a week, Also I have high blood pressure and i am taking losar 25 every day. My age is 31, How could I lower the levels of SGPT and bilirubin ?
Mon, 16 Dec 2013
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Internal Medicine Specialist 's  Response
Hi there,

Thanks for your query.

Bilirubin level of 0.25mg% is PERFECTLY WITHIN NORMAL RANGE.

All drugs (including Losartan) belonging to the class of Angiotensin Receptor Blockers cause transient elevation of liver enzymes, including SGPT.

However, the levels of SGPT are not of much alarm.

Switching over to a drug belonging to another class will revert SGPT levels to within normal range.

Consult your doctor and apprise him of my opinion. I am certain that he will agree with me, order required tests, and- based on the reports- will prescribe suitable/modified treatment as advised.

In case of any further queries, revert back to me THROUGH DIRECT PREMIUM QUERY (Paid), addressed to me personally. You will receive- almost immediately- my response in great details.

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Fond regards and have a nice day

Dr. Rakesh Karanwal
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Pathologist and Microbiologist Dr. Vandana Khare's  Response
welcome to HCM!
The normal range of values for ALT (SGPT) is from 7 to 56 units per liter of serum.Your SGPT is high but bilirubin is normal.SGPT is sensitive indicator of liver damage or injury,alcohol can be a cause.Losartan usually has no bad effect on liver unless liver function is already compromised.Hope this helps!Take care!
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