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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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RA Factor 320. Anti CCP, ANA, ACE, HLA Negative. Having Occasional Joint Pains, Psoriasis, Chest Pain, Allergy Attacks. RA Or PSA?

I am 36 my RA factor is 320. I had done tests like Anti-CCP, ANA, ACE, HLA etc... all came negative. I have small joints pains occasionally. I have skin psoriasis like behind my ear, and chest pain , allergy attacks. I felt watery mouth also and dryness in eyes. Doctor asked me to have SAAZ thrice a day. Do I have RA or PSA?
Thu, 7 Feb 2013
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General & Family Physician 's  Response
Hello,
Rheumatoid factor (RF) is a blood test that measures the amount of the RF antibody in the blood.
Most patients with rheumatoid arthritis, and almost all patients with Sjogren syndrome have positive RF tests.
However, not everyone with higher levels of rheumatoid factor has rheumatoid arthritis or Sjogren syndrome.
People with the following diseases may also have higher levels of rheumatoid factor:
Scleroderma
Systemic lupus erythematosus
Dermatomyositis
Sarcoidosis
Higher-than-normal levels of RF may be seen in people with other medical problems. However, these higher RF levels cannot be used to diagnose these other conditions.:
AIDS, hepatitis, influenza,  and other viral infections
Certain kidney diseases
Endocarditis, tuberculosis, and other bacterial infections
Parasite infections
Leukemia, multiple myeloma, and other cancers etc
Sometimes, people who are healthy and have no other medical problem will have a higher-than-normal RF level.

Since you don't have persistent pain and swelling in your joints and anti CCP antibodies etc are negative,other causes should be looked into.
Thanks
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Rheumatologist Dr. Divya Agarwal's  Response
Actually you may not be having either becoz for these you need to be having persistent joint pain and swelling.
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Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
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RA Factor 320. Anti CCP, ANA, ACE, HLA Negative. Having Occasional Joint Pains, Psoriasis, Chest Pain, Allergy Attacks. RA Or PSA?

Hello, Rheumatoid factor (RF) is a blood test that measures the amount of the RF antibody in the blood. Most patients with rheumatoid arthritis, and almost all patients with Sjogren syndrome have positive RF tests. However, not everyone with higher levels of rheumatoid factor has rheumatoid arthritis or Sjogren syndrome. People with the following diseases may also have higher levels of rheumatoid factor: Scleroderma Systemic lupus erythematosus Dermatomyositis Sarcoidosis Higher-than-normal levels of RF may be seen in people with other medical problems. However, these higher RF levels cannot be used to diagnose these other conditions.: AIDS, hepatitis, influenza,  and other viral infections Certain kidney diseases Endocarditis, tuberculosis, and other bacterial infections Parasite infections Leukemia, multiple myeloma, and other cancers etc Sometimes, people who are healthy and have no other medical problem will have a higher-than-normal RF level. Since you don t have persistent pain and swelling in your joints and anti CCP antibodies etc are negative,other causes should be looked into. Thanks