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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Pulmonary tuberculosis,sputum examination negative, taking Fixcom 4, orange urine, itchy

I have some question I just starting taking my first dose this morning. they found out in my x ray result that I had PTB but i my sputum examination result is negative. so doctor instruct me take the Fixcom 4 so my urine is orange and i has itch a little. I cannot contact her right now because its holiday in. so I need a advise from you.
Fri, 11 May 2012
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General & Family Physician 's  Response
Hello lynz.pisces. Welcome to

Continue taking your medication for the recommended amount of time. Pulmonary tuberculosis (TB) is resistant to many medications. The medication you are taking, Fixcom 4, is a combination of rifampin, ethambutol, pyrazinamide, and, isonizaid. The rifampin portion of this medication will change the color of bodily fluids (urine and tears) to an orange/red color. If you wear contacts, it will stain your contacts.

Any time that you take antibiotics, it will change your body chemistry, which is probably the cause of your pruritis (itching). However, if you should experience hives, swelling of your lips, tongue, face, and have difficulty breathing; go to the nearest emergency room for treatment.

It is very important to continue your medications as prescribed by your physician.

Be well, Dr. Kimberly
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