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Prescribed with Encorate chrono for a seizure. Feeling weak and drowsy. Need help in correcting the dosage

my grand mother who is 80 years old, suffered a seizure 3 days ago, the doctor prescribed her encorate chrono 200 mg twice daily, she feels weak and drowsy, my question is, is the weakness and drowsiness because of the extra dosage, should i reduce the dosage to 100 mg each in the morning and night, considering her age.
Asked On : Mon, 24 Sep 2012
Answers:  1 Views:  61
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Neurologist 's  Response
Nov 2013

Thank you for posting your query.

Encorate chrono is a safe and effective medication for treating fits. The dose depends on the body weight- 15 to 60 mg per kg body weight. So, the dose of 200 mg twice daily (total dose per day of 400 mg) is quite low.

If you still feel that the drowsiness is because of the overdosage of encorate (sodium valproate), we can do a blood test to look for its level- serum valproate level. If found high, the dose may be reduced or stopped altogether and replaced with another medicine such as phenytoin.

Best wishes,
Dr Sudhir Kumar MD DM (Neurology)
Senior Consultant Neurologist
Answered: Wed, 13 Feb 2013
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