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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Pregnant, have severe itching, prescribed Udiliv, advised liver test. Is it safe to have this tablet during pregnancy?

i am 7 months pregnant. I have sever itching sensation( statrted in stomach and gradually psread in hands and now in legs and some parts of body) and i have been prescribed to take UDILIV 300 both in morning and in evening for 15 days. Is it safe to have that tablet during pregnancy? i have been asked to undergo a liver test also. is ithis itching common during pregnancy? if i take udiliv 300 tablet, will it affect by child? Seeking your advise adn suggetsion. Regards Vandhana Srinath
Tue, 28 Aug 2012
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Endocrinologist 's  Response
Hi Vandhana,

considering your history and the drug you have been prescribed, you have been probably diagnosed to have intrahepatic cholestasis of pregnancy.

Intrahepatic cholestasis of pregnancy (ICP) occurs in the second and third trimester, and is characterized by itching and an elevation in serum bile acid concentrations. The onset of ICP is typically heralded by the development of itching, which may be intolerable. It is often generalized but predominates on the palms and the soles of the feet, and is worse at night

You need to get done an Ultrasound of abdomen, Liver functions tests and viral markers (Hepatitis B, C, A and E) before we can make this diagnosis.

If the diagnosis is correct, udiliv is the correct medication for this. It is safe in pregnancy and trials done have shown no harm to fetus or mother.

Please let me know the results of above tests and we can determine if you need to continue the treatment or not.

Thanks
Regards
Dr. Om Lakhani
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General & Family Physician Dr. Sourav Ganguly's  Response
Hi,
Thanks for your query.
you have been probably diagnosed to have intrahepatic cholestasis of pregnancy.
Udilive is bile salt lowering agents and absolutely safe in pregnancy.

Best wishes
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Pregnant, have severe itching, prescribed Udiliv, advised liver test. Is it safe to have this tablet during pregnancy?

Hi Vandhana, considering your history and the drug you have been prescribed, you have been probably diagnosed to have intrahepatic cholestasis of pregnancy. Intrahepatic cholestasis of pregnancy (ICP) occurs in the second and third trimester, and is characterized by itching and an elevation in serum bile acid concentrations. The onset of ICP is typically heralded by the development of itching, which may be intolerable. It is often generalized but predominates on the palms and the soles of the feet, and is worse at night You need to get done an Ultrasound of abdomen, Liver functions tests and viral markers (Hepatitis B, C, A and E) before we can make this diagnosis. If the diagnosis is correct, udiliv is the correct medication for this. It is safe in pregnancy and trials done have shown no harm to fetus or mother. Please let me know the results of above tests and we can determine if you need to continue the treatment or not. Thanks Regards Dr. Om Lakhani