Hello Dr Priya
Welcome to HCM

Thyroid disorders are known to flare up during pregnancy.
Whether prgnancy stimulates auto-immunity is not proven.
But what is impotant during pregnancy is to mainatain normal levels of T3 and T4 during pregnancy because these hormones play an impotant role in the brain development of the fetus especially during first trimester.
So, in face of hypothyroidism continue levothroxine and get the levels of T3 and T4 regularly.

Whether you will require treatment after delivery wil be guided by your TSH levels at that point of time.
PCOS will not have any effect on your current pregnancy.

I hope it helps.
Dr Shailja P Wahal

Hello
thanks for the query.
pregnancy does affect autoimmune functions.
But if you are TPO positive, that cannot happen suddenly.
Was your TPO also normal before pregnancy, or were only thyroid functions done.
As you might be aware, TSH of 17 is quite raised, and periconceptional TSH is recommended to be below 2.5.
So it might affect the fetus as it is the crucial time of development, and also lead to preterm labour and obstetric adverse effects for the mother, if untreated.
You should consult an endocrinologist, and start the appropriate dose of levothyroxine, and alongwith that monitor the TSH to maintain it to 2.5 or less.
Most patients need lifetime therapy, and autoimmunity further increases that chance.
Also, PCOS compounds the effects of hypothyroidism, you should also take adequate calcium and vitamin D supplementation in the second trimester.
Take care