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Peripheral blood smear shows normocytic, slightly hypochromic RBCs. Meaning?

Im 41 yrs old female..what does it mean it your peripheral blood smear report show normocytic slightly hypochormic red blood cells with slight variation in size and shapes..the white blood cell count is within normal limits with predominance of segmenters.. The differential count is: Sementers. -0.68, bands/stabs - 0.03, lymphocytes- 0.27, monocytes-0.01, eosinophils -0.01.. Thanks
Asked On : Thu, 21 Mar 2013
Answers:  2 Views:  1252
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Internal Medicine Specialist 's  Response

Thanks for being with HCM.

Normocytic hypochromic red blood cells means red blood cells size is normal but amount of hemoglobin inside the cells is less.

Slight variation in size and shape that is also called anisocytosis and poikilocytosis.Such type of change is also due to decreased hemoglobin concentration or defect in formation of cell membranes.

You need not to go into details of these changes.These changes can be seen in:
1.iron deficiency anaemia
2.chronic blood loss due to peptic ulcer,hemorrhoids,heavy menstruation,etc
3.Anaemia of chronic disease such as chronic kidney disease,tuberculosis,malabsorption.

Rest of the findings mentioned in report are normal.

Now my question is, how much is your hemoglobin?
If you have low hemoglobin, get physician's opinion for cause of you low hemoglobin.
There is possibility of iron deficiency as all the changes mentioned in report are seen in iron deficiency anaemia.It is most common cause for such findings.You may need iron supplement to correct it.

Hope i could help you better.Do not hesitate to write us for more queries.

Wish you good health.

Answered: Fri, 22 Mar 2013
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Pulmonologist Dr. Jabeed P's  Response
The blood report indicates that the red blood cells are normal in size but slightly underpigmented.
The amount of Hemoglobin ( oxygen carrying pigment) in each blood cell is slightly less.
The slight variation in size and shapes ( anisopikilocytosis) also indicates low Hemoglobin ( anemia)
Most probably you are not getting sufficient iron from your diet.
Or you may be losing blood ( excessive menstrual bleeding or worm infestation )
Answered: Fri, 22 Mar 2013
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