Hello, Raised ESR or erythrocyte sedimentation rate is a test done to exclude underlying inflammation in the body. It also goes up in infections, and when the hemoglobin is low (i.e., anaemia). Raised ESR (persistent) result suggests you need to exclude the above conditions mentioned. Follow up blood tests: Complete hemogram (Hb, TC DC) CRP Liver function tests Urea, creatinine Serum protein electrophoresis Chest X Ray Antinuclear antibody Now all of the above tests would exclude common serious pathologies, so please get them done after discussing with your doctor as soon as possible. Best Wishes.