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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Not talking normally, diabetic. Is it safe to take bupropion and fluoxentine while smoking weed?

can you take the drug bupropion and fluoxetine together along with smoking weed. My husband takes both of these drugs plus hydralazine and he is talking out of his head he is making no since at all he is also a diabetic he is not eating or sleeping this just started a few days ago. Before he started talking crazy his blood sugar and blood pressure was bouncing all over the place
Thu, 22 Aug 2013
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Psychiatrist 's  Response
Hello
Welcome to HCM

Bupropion and Fluoxetine are anti depressant drugs. These drugs tend to cause CNS activation. Bupropion even increases Dopaminergic neurotransmission and taking weed or opium with bupropion will cause precipitation of psychotic symptoms. These both drugs may cause psychomotor agitation. So as per my opinion it is not advisable to take weed together with these drugs.

Hope it helps you, thanks
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