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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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My Son Has Nephrotic Syndrome.

My 5 years old son has Nephrotic Syndrome since August 2010. Since then Prednisone 45mg has been given on daily basis. As a result his weight has risen up to 31 kg from 24 kg. He has swelling as well. He recently started taking Cyclophosphamide 75mg daily (3 weeks before) along with 40mg Prednisone every alternate day. But his protein discharge level is continued to ++ (based of strips test early morning first urine). Almost daily he complains headache and his hair have started falling. Please suggest what to do in this case and how long it will take my son to get rid of this problem? Thanks.
Fri, 1 Apr 2011
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General & Family Physician 's  Response
Hi Kashif, Welcome to Healthcare Magic Forum.
The symptoms your child is experiencing are the side effects of the medicines he is on. Don't worry about the side effects as the condition needs first priority, just see to it that he take the medicines regularly as directed by your Doctor and take him for regular follow up.
The outcome of the disease varies, the syndrome may be acute and short term or chronic and unresponsive to therapy. The cause and development of complications also affect the outcome. A low salt diet may help with swelling in the hands and legs.
Good Luck.
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Kashif Javed's  Response
Hi Doctor, thanks for your prompt reply.
I have a question. At a time when my son was taking Prednisone 45mg daily, his protein discharge level was always + and very few times nil. His doctor suggested that this medicine must not be given for such a longer period of time (i.e. 6 months). Now the doctor is gradually reducing Prednisone. As a result his protein level is always ++ even after taking 75mg Cyclophosphamide daily. Does this three weeks analysis not showing that the new medicine is not suitable for him? Also, he passes urine more frequently that normal. What is its cause? Thanks.

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My Son Has Nephrotic Syndrome.

Hi Kashif, Welcome to Healthcare Magic Forum. The symptoms your child is experiencing are the side effects of the medicines he is on. Don t worry about the side effects as the condition needs first priority, just see to it that he take the medicines regularly as directed by your Doctor and take him for regular follow up. The outcome of the disease varies, the syndrome may be acute and short term or chronic and unresponsive to therapy. The cause and development of complications also affect the outcome. A low salt diet may help with swelling in the hands and legs. Good Luck.