Hi,
Welcome to HCM
There are few important points in your history,
Rapid weight loss, Extreme
fatigue and Loss of appetite and appearance of hard nodule warrants to get urgent action.
Please arrange for consultation with surgeon.
As there is family history of G I malignancy A internal examination with Ultra
sonography, along with CBC, LFT,and Kidney function test,some tumor markers CEA (Carcino Embryonic Antigen) and AFP (Alfa feto Protein), may give clue to diagnosis.
A
colonoscopy with
biopsy if they find any lesion.
Once diagnosis is confirmed treatment can be planned accordingly.
In the mean time take care of your diet .
Take care.
Best of Luck.