Hello, Thanks for using healthcare magic for posting your query. Knee pains cause of arthritis with degeneration of the cartilage in the knee joint is a very common condition and unfortunately very painful one too. It restricts your mobility a lot and also impairs your activities of daily living. Coming to the treatment part, the first concern should be to reduce the weight. Less the weight the knees have to handle, less the pain. There are a couple of exercises which your physiotherapist more than happy to help you with which will strengthen your musculature around the knee and reduce the pain. Coming to the drugs, glucosamines are good drugs and have made their way into allopathy since many years. They try to improve the condition of the cartilage and thereby reduce the pain. Knee replacement is the last option but recently the procedure has become safe and is becoming more and more popular. But then financial concerns are there as the procedure and the prosthesis are very costly. Hope I ma able to solve your concerns. Thanks. Hope your mother gets well soon.