Hi,A About 4 years ago i started taking Venlafaxine. It did a good job of addressing my feelings of depression. A friend told me that it s difficult to come off Venlafaxine and that I should talk to my healthcare provider about the idea of introducing Wellbutrin while reducing the venlafaxine. While taking venlafaxine alone I had some pretty typical side effects; I gained weight steadily since starting the venlafaxine and I have very strange dreams. My mood was definitely positively effected with this medication though. I recently stopped taking venlafaxine all together. I have been experiencing typical side effects like blurry vision, buzzing in my brain, and I m now getting pretty agitated. Before I didn t feel irritable, was pretty calm and happy. I m now feeling anxious, ealiy frustrated, irritable etc. I m super frustrated about the weight gain that i have had over the past four years, however, i m wondering if it would make sense for me to go back on venlafaxine if i m going to be grouchy. Also - my healthcare provider did suggest that I increase my wellbutrin from 300 to 450 now that I m off venlafaxine. I haven t increased the amount yet. I m wondering if it is likely that the increase in Wellbutrin will address the issues I m now experiencing. I look forward to hearing your thoughts on this situation. thank you, Stephanie