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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is there any treatment to cure crigler najjar syndrom type 2 ?

hello doctor! i m 13 yrs old and i have crigler najjar type 2.i got it from my dad and have it since birth .i dont have anyother problems. my full body looks yellow and i dont like it. i have done liver check up and ultrasound too.everything is normal.only my billirubin is high.i m taking phenobarbitone.i dont want to look yellow. is there any treatment for it other than phenpbarbitone.
Tue, 31 Jan 2012
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General & Family Physician 's  Response
Hello.Welcome to HCM forum.it is an inherited cause of unconjugated hyperbilirubinemia presenting in the first days of life with jaundice and with or without CNS symptoms.The ultimate treatment is liver transplant before irreversible kernicterus develops.Till then carry on with phenobarbitone.Thanks and good luck.
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Orthopaedic Surgeon Dr. Aashish Raghu's  Response
Welcome to Healthcare Magic
Phenobarbitone is a common method to treat Type II Criggler Najar syndrome. Not many therapeutic regimen exist but blood transfusion at intervals can help to some extent. You need to avoid smoking and alcohol. Get your liver function tests and other tests done if you are having recent appearance of yellow colour from before to rule out other conditions which can cause jaundice like Hepatitis as well.
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Is there any treatment to cure crigler najjar syndrom type 2 ?

Hello.Welcome to HCM forum.it is an inherited cause of unconjugated hyperbilirubinemia presenting in the first days of life with jaundice and with or without CNS symptoms.The ultimate treatment is liver transplant before irreversible kernicterus develops.Till then carry on with phenobarbitone.Thanks and good luck.