Thank you for the query. Steroid creams are topical corticosteroid preparations, which are devoid (or may mildly produce), the systemic side effects of steroids. Some side effects of local steroids are, burning/stinging of the skin, skin colour changes, thinning (atrophy) of the skin and flaring/worsening of any old infection of skin. The systemic effects are Hyperglycemia (increased blood sugar), osteoporosis, weight gain and high blood pressure (though these are unlikely with steroid creams). Systemic steroids are more likely to cause menstrual cycle disturbances. In this context I would also like to know the preparation of local steroid cream that you are applying. Delayed menstrual cycle after application of local steroid cream for eczema is not very likely. I would want to know your height and weight (BMI) and if you continue to have delayed, irregular menstrual cycle, you must consult your gynaecologist, to rule out other conditions like Polycystic Ovarian Disease. Hope this helps you out.