lipoprotein subfraction and LDL sub fraction testing is not diagnostic test. The test evaluates LDL particles according to their number, size, density, and/or electrical charge. It may offer useful information for assessing risk in people who have a personal or family history of heart disease at a young age, especially if their total and LDL cholesterol (LDL-C) values are not significantly elevated. It may also be occasionally ordered to monitor the effectiveness of treatment. The result is interpreted within the framework of a lipid profile and its associated risk. If a person has a large number of primarily small, dense LDL and an increased LDL-P, this finding will add to the individual s risk of developing CVD above and beyond the risk associated with the total LDL.