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Duphaston contains dydrogesterone
) and it is one of the safe drugs used frequently in gynecology practice. Dydrogesterone helps regulate the healthy growth and normal shedding of the uterus lining. It should not be used in females with history of breast cancer
. There is risk of breast cancer only when duphastone is used with estrogen in hormone replacement therapy
(HRT) for post menopausal woman. On its own it doesnt have any risk of breast cancer. Breast tenderness is a side effect of duphastone but not cancer. Take care.