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is a allergic reaction
and can be due to food allergy;dust and pollens;mites in bed;insect bite;and even dry skin
can result in such a condition.It is a difficult to treat condition.At age of 45 yrs or more in females there can be few hormonal
changes(close to menopause
or at menopause) in the body which can result in dryness of skin or change in texture of skin which may be causing allergy.Please try to locate the allergy causing factor and get treatment from a Skin specialist.The best treatment is only possible after the proper diagnosis of allergy causing thing.
wish her a speedy recovery.