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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Klinefelter Syndrome And Azoospermia Curable?

Hello Doctor
My husband is diagnosed with klinefelter syndrome non mosaic(probably) and underwent a tissue biopsy which reported no sperms but atrophic and hyalonised sertoli cells and stroma with leydig cells. is he treatable to produce sperms and father his own biological child?
Fri, 7 Nov 2014
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Radiologist 's  Response
Hi welcome to healthcaremagic.
I have gone through your question.
In klienfelter syndrome if there are no sperms or azoospermia due to damage to sertoli cells then its impossible to retrieve.
As these cells can not be regenerated or it can not produce sperms now.
So he cant become father on his own.
Hope i answered your question.
Would be happy to help you further.
Take care.
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Is Klinefelter Syndrome And Azoospermia Curable?

Hi welcome to healthcaremagic. I have gone through your question. In klienfelter syndrome if there are no sperms or azoospermia due to damage to sertoli cells then its impossible to retrieve. As these cells can not be regenerated or it can not produce sperms now. So he cant become father on his own. Hope i answered your question. Would be happy to help you further. Take care.