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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Take Pavix Along With Nexium Taken For GERD And Baretts Esophagus ?

I ve been on NEXIUM RX for many years for GERD and Barrett s esophagous and I feel great. Also, I have begun taking clopidigril (Plavix) for a few months, but I read that Nexium and Plavix should not be taken together. Can I take PRILOSEC RX instead of Nexium and will it work the same ??
Mon, 11 Feb 2019
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Internal Medicine Specialist 's  Response
Hello,

Both should not be taken together. Pharmacodynamic studies suggest that Omeprazole can attenuate the antiplatelet effect of clopidogrel.

This interaction does not appear to translate into increased cardiovascular risk in patients treated with this combination. Other PPI not interact much. So you can take alternate PPI s.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Penchila Prasad Kandikattu , Internal Medicine Specialist
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Is It Safe To Take Pavix Along With Nexium Taken For GERD And Baretts Esophagus ?

Hello, Both should not be taken together. Pharmacodynamic studies suggest that Omeprazole can attenuate the antiplatelet effect of clopidogrel. This interaction does not appear to translate into increased cardiovascular risk in patients treated with this combination. Other PPI not interact much. So you can take alternate PPI s. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Penchila Prasad Kandikattu , Internal Medicine Specialist