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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is It Safe To Resume On Blood Thinners To Avoid Further Blood Clots?

My husband had a few TIA s about eight years ago and was placed on blood thinning medication. He was diagnosed with cerebral amyloid angiopathy two years ago and taken off the blood thinners. He has now developed a pulmonary embolism and was given shots of blood thinners. The question is whether to resume the blood thinners to prevent further blood clots, but risk the brain bleeds associated with CAA.
Mon, 28 Nov 2016
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General & Family Physician 's  Response
Dear Madam, Hi & Welcome.

I appreciate your concern for your beloved husband and who is diagnosed to have a condition called cerebral amyloid angiopathy.

In general it is not safe to take "blood thinners" while suffering from this condition.

It is a disease of blood vessels of the brain in which amyloid (a protein) gets deposited as a part of common aging process and is usually harmless.

However, it may damage the delicate blood vessels in the brain causing bleeding or hemorrhagic stroke.

Anti-clotting medications ("blood thinners") like Warfarin should not be used to prevent thromboembolism because of a high risk of bleeding result from it.

Unfortunately there have been no medicines yet shown to lower the risk of recurrent bleeding in patients suffering from cerebral amyloid angiopathy.

The decision regarding the use of blood thinners to prevent thrombo-embolism (pulmonary embolism) should be taken carefully by his treating doctor by estimating the benefits versus risks, if at all low dose Aspirin or Clopidogrel may be considered if the situation is critical.

Beside, his BP should be carefully monitored to reduce the risk of bleeding and maintained it within the normal range.

Hope these answer your queries.

Wishing your husband a very good health/.
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Is It Safe To Resume On Blood Thinners To Avoid Further Blood Clots?

Dear Madam, Hi & Welcome. I appreciate your concern for your beloved husband and who is diagnosed to have a condition called cerebral amyloid angiopathy. In general it is not safe to take blood thinners while suffering from this condition. It is a disease of blood vessels of the brain in which amyloid (a protein) gets deposited as a part of common aging process and is usually harmless. However, it may damage the delicate blood vessels in the brain causing bleeding or hemorrhagic stroke. Anti-clotting medications ( blood thinners ) like Warfarin should not be used to prevent thromboembolism because of a high risk of bleeding result from it. Unfortunately there have been no medicines yet shown to lower the risk of recurrent bleeding in patients suffering from cerebral amyloid angiopathy. The decision regarding the use of blood thinners to prevent thrombo-embolism (pulmonary embolism) should be taken carefully by his treating doctor by estimating the benefits versus risks, if at all low dose Aspirin or Clopidogrel may be considered if the situation is critical. Beside, his BP should be carefully monitored to reduce the risk of bleeding and maintained it within the normal range. Hope these answer your queries. Wishing your husband a very good health/.