Hello and welcome, I found the query unanswered since a few days and so chose to answer it despite it being addressed to Dr Samuel. Pregnancy usually is well tolerated except that nausea and vomiting of pregnancy may lead to starvation and precipitate attacks. So take care to avoid these during pregnancy. Certain drugs must be avoided and you have to inform your doctor about this. Also since this is a genetic defect there is a 50% chance of child born with porphyria. So you may go ahead with pregnancy. Hope this satisfies your query. Thanks for using HCM. Feel free to ask any more questions that you may have. Dr Madhuri Bagde Consultant Obstetrician and Gynecologist