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Dr. Andrew Rynne

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Exp 50 years

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Is it safe for IUI procedure at 14 day of period, primolut was given for 16 to 25 days?

I am a 29 year old, diagnosed with PCOS, and have irregular menses.Been trying to conceive and carried out an IUI procedure recently after a basl temperature drop- sign of Ovulation.Usually when i take Primolut,it induces bleeding.But my Doc prescribed it for Day 16-25 of period.Is it safe even after IUI procedure @ day 14?
Wed, 2 Nov 2016
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OBGYN 's  Response
Hallow Dear,

If you are a case of PCOS, you should not go for IUI empirically. Just do not go by temperature changes in the Basal Body Temperature Chart; some other relevant information is important and required before attempting any Artificial Reproductory Technique like IUI.

In patients with regular menstrual cycle, day of ovulation is 14 days before the expected menstrual cycle. However, since you are a PCOS case, your menses must be irregular. Hence, better not rely on day 14 of the cycle.

I would advise you to go for ultrasonography ovulation monitoring. It will help following way:

1. It will precisely detect the day of ovulation when you can go for Intrauterine Insemination (IUI).

2. It will inform us about the size of the follicle when it ruptured to release the egg. Follicles of size between 18 mm to 21 mm release the healthiest eggs having good chances of successful pregnancy.

3. If the eggs are not getting released naturally (which is characteristic of PCOS), your Gynaecologist can plan induction of ovulation by some medicines like Clomiphene citrate or HMG/HCG combination and then plan IUI accordingly. May be you might require Metformin or Myo Inositol as an adjuvant therapy.

4. Ultrasonography will inform us about the development of the uterine cavity lining (endometrium). Endometrium of thickness between 9 mm to 14 mm is most conducive for implantation of fertilized egg. If the endometrium is thin, your IUI may go waste.

Hence, please submit yourself for ovulation monitoring from by Ultrasonography day 9 of the cycle and then plan for IUI.

Please do not take Primolut pills for regularizing the menses; they may interfere with the egg release. Ovulation induction medicines will regularise your menses along with the induction of ovulation.

Please report to some Infertility Consultant.

I hope you got the message.

Dr. Nishikant Shrotri
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