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Dr. Andrew Rynne
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is it advisable to take Cyclo Progynova therapy?

Hi! I m 28 years old and truing to get pregnant for the first time with my husband. My doctor prescribed me 3 months of Cyclo Progynova therapy, because we are trying for the last year or so. My cycles are somewhat ok, but we suspect that maybe my follicular phase is a bit longer (I suspect the ovulation is on 16th or 17th day from the beginning of the period). Is my doctor right and should I go along with this therapy even though I read a lot about side effects?
Mon, 25 Jan 2016
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OBGYN 's  Response
Hallow Dear,

Cyclo Progynova comes in two forms, white tablets are estradiol valerate while pale brown tablets are estradiol valerate with norgestrel. These pills are good for hormone replacement therapy in menopausal women. They will regularise your menstrual cycles in you; however they cannot help you to conceive. In fact they may stop the ovulation.

Have you undergone the investigations to assess your ovulation, patency of the tubes and semen examination?

If ovulation is the problem, Clomiphene citrate tablets may help you; may be in association with Metformin. Before taking these tablets, first get your ovulation monitoring done by ultrasonography. If it reveals that you are not ovulating, then only go for these tablets.

However, your history informs that you are ovulating on 16-17 day of cycle. Ovulation on day 16 is not a problem so long as the secretory phase is 14 days. If it is shorter, you may require progesterone supplementation in secretory phase to help good implantation and support to the pregnancy.

If there is no problem with your ovulation and secretory phase, the cause of non-conception could be in the tubes or with husband. Please get Hysterosalpingography done for your tube testing and also husband's semen examination. The reports of these investigations may demand for different line of treatment.

After complete investigations, you may ask me Direct question for further follow up discussion and advice.

I hope this gives you guidance.

Dr. Nishikant Shrotri
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