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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Active Hepatitis C Congenital And Is It Hereditary?

My daughter's boyfriend has active hepatitis C. What is the risk to her? He states he was born with it and last treated around the age of 7. I'd like to believe him. He is clean cut, a good college kid who doesn't party, etc. We encouraged him to be re-tested and it's showing active and he's starting treatment once a week for nearly a year - how will this affect him and their relationship? I'm very concerned about the risk to her health. I understand it's low but I'm still very scared. She's 18 and I'm not sure she understands the importance of protection and that she needs to take it seriously and protect her own health. Also, if he was born with it, is it something that can be passed on to his future children?
Tue, 1 Jul 2014
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General & Family Physician 's  Response
Hello
This is very crucial thing so I will try to explain , what is written in Harrison's test book about "hepatitis C".
Chronic hepatitis C follows acute hepatitis C in 50-70 % of cases ;even those with a return to normal in aminotrnsferase levels after acute hepatitis C, chronic infection is common, adding up to an 85-90% likelihood of chronic HCV infection after acute hepatitis C. Please note down that relapse is common in 85-90 % cases even aminotransferase levels normal .
Such is the case even for patients with relatively clinically mild chronic hepatitis including those without symptoms , with only modest elevation of aminotransferase acitivity, and with mild chronic hepatitis on LIVER biosy.
Even in cohorts of well-compensated patients with chronic hepatitis C referred for clinic researc trials , the prevalence of "cirrhosis "may be as high as 50%.
As I mentioned in above case ,there is a great risk and danger .
No doubt fetus in uterus may be in high risk group for hepatitis C infection .
Hope this information will be helpful .
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Is Active Hepatitis C Congenital And Is It Hereditary?

Hello This is very crucial thing so I will try to explain , what is written in Harrison s test book about hepatitis C . Chronic hepatitis C follows acute hepatitis C in 50-70 % of cases ;even those with a return to normal in aminotrnsferase levels after acute hepatitis C, chronic infection is common, adding up to an 85-90% likelihood of chronic HCV infection after acute hepatitis C. Please note down that relapse is common in 85-90 % cases even aminotransferase levels normal . Such is the case even for patients with relatively clinically mild chronic hepatitis including those without symptoms , with only modest elevation of aminotransferase acitivity, and with mild chronic hepatitis on LIVER biosy. Even in cohorts of well-compensated patients with chronic hepatitis C referred for clinic researc trials , the prevalence of cirrhosis may be as high as 50%. As I mentioned in above case ,there is a great risk and danger . No doubt fetus in uterus may be in high risk group for hepatitis C infection . Hope this information will be helpful .