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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is A Major Drop In Progesterone Level Harmful For The Fetus?

I am currently 10 weeks and 4 days pregnant and have two previous miscarriages, both occured at 6 weeks. I have had an ultrasound every two weeks. My latest was last week at 9 weeks and 3 days and showed a the baby and we heard a healthy heartbeat at 164 BPM. I am currently on 600 mg of oral prometrium daily and the doctor has my progesterone taken daily. My first Progesterone taken was 14 and then dropped to 13 then went up to 39 and my most recent was t 10 weeks and it had dropped to 22.5 so he increased my prometrium to 800 mg of prometrium yesterday. I guess I am looking for a little reassurance hopefully. I am worried, and wondering if this is normal or should I be worried that there might be something wrong since my progesterone dropped so much. I know it is normal for progesterone to fluctuate but I feel like that was a major drop. I go back Monday for another blood draw and have an ultrasound schedule next weds. Your feedback and advice would be greatly appreciated. Ashlee
Mon, 25 Jan 2016
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OBGYN 's  Response
Dear Ashlee,

Your thinking is absolutely logical.

Progesterone is a hormone which (as it its name suggests) is necessary for maintenance of pregnancy. It has got many functions, however, an important one is to relax the uterus and let it not go into labour contractions prematurely. If the levels of this hormone are dropping down substantially, your doctor has very scientifically increased the dosage of Progesterone.

I hope this helps you. I wish, Progesterone will take your pregnancy to term to give you a bonny baby to breastfeed.

Dr. Nishikant Shrotri
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Is A Major Drop In Progesterone Level Harmful For The Fetus?

Dear Ashlee, Your thinking is absolutely logical. Progesterone is a hormone which (as it its name suggests) is necessary for maintenance of pregnancy. It has got many functions, however, an important one is to relax the uterus and let it not go into labour contractions prematurely. If the levels of this hormone are dropping down substantially, your doctor has very scientifically increased the dosage of Progesterone. I hope this helps you. I wish, Progesterone will take your pregnancy to term to give you a bonny baby to breastfeed. Dr. Nishikant Shrotri