Hi,I am Dr. Subhankar Chakraborty (Gastroenterologist). I will be looking into your question and guiding you through the process. Please write your question below.
I'm taking methotrexate for RA. My hepatic panel shows SGPT of 108. I understand this is higher than the norm but is this level cause for concern? I have a MD appointment on 11/29. Can I wait until then or should I schedule for an earlier appointmenrt?
Increased SGPT may indicate liver injury and it may be due to methotrexate therapy. You may need dose adjustment of methotrexate. You may need tablet ursodeoxycholic acid tablet 300 mg twice daily for three months. Ursodeoxycholic helps in regeneration of liver cells. You may also need ultrasonography of abdomen to exclude other causes.
Get well soon. Take Care Dr.Indu Bhushan
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Is SGPT Of 108 A Cause For Concern?
Hello Increased SGPT may indicate liver injury and it may be due to methotrexate therapy. You may need dose adjustment of methotrexate. You may need tablet ursodeoxycholic acid tablet 300 mg twice daily for three months. Ursodeoxycholic helps in regeneration of liver cells. You may also need ultrasonography of abdomen to exclude other causes. Get well soon. Take Care Dr.Indu Bhushan