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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Prednisone Effective In The Treatment Of Allergic Rashes?

I am taking my second month's pills of amlodipine for high blood pressure. It has brought
the bp down considerably, but I have a rash over legs, throat, under arms and also have
some swelling in my legs around ankle area. My doc has put me on prednisone. Will
this stop the rash within a week, or how many days? Linda Runyon
Tue, 17 Oct 2017
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General & Family Physician 's  Response
Although calcium-antagonists can be ,and often are,useful in treatment of hypertension,the most common side-effect is leg swelling (often misinterpreted as sign of cardiac/kidney failure). If the rash does not disappear within 2 weeks,or it reappears within a few days without prednisone,in my opinion,it would be wise to change your antihypertesive to another calcium-antagonist, or some from completely different group of AHT (examples are beta blockers, ACE inhibitors/blockers........). Especially since prolonged use of corticosteroids may cause hypertension! In my experience even a change within the same AHT group can lead to swellings and rash disappearing,and in that manner can contribute to more comfortable and regular use of antihypertensive drug,evenmoreso since it is about prolonged,possibly lifelong use. Best regards!
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Is Prednisone Effective In The Treatment Of Allergic Rashes?

Although calcium-antagonists can be ,and often are,useful in treatment of hypertension,the most common side-effect is leg swelling (often misinterpreted as sign of cardiac/kidney failure). If the rash does not disappear within 2 weeks,or it reappears within a few days without prednisone,in my opinion,it would be wise to change your antihypertesive to another calcium-antagonist, or some from completely different group of AHT (examples are beta blockers, ACE inhibitors/blockers........). Especially since prolonged use of corticosteroids may cause hypertension! In my experience even a change within the same AHT group can lead to swellings and rash disappearing,and in that manner can contribute to more comfortable and regular use of antihypertensive drug,evenmoreso since it is about prolonged,possibly lifelong use. Best regards!