Hello dear, Thank you for your question and welcome to Healthcare Magic. I read your question and I understand your concern. Actually Glycomet (metformin) has shown very effective action in both PCOS and helping weight lose. Normally, metformin is used in balancing blood sugar in type 2 diabetes, but different studies has shown that is has also very positive effects in treating symptoms in PCOS because it helps lowering testosterone production. It slows the growth of abnormal hair and, after a few months of use, it may help ovulation to normalise. Recent research has shown metformin to have other positive effects, such as decreased body mass and improved cholesterol levels. Regarding your thyroid problems, you do not mention what kind of disorder you might have, but I guess it is hypothyroidism, due to your body weight. In order to help yourself to gain your desired body weight, you have to balance also your thyroid hormone level, by taking the appropriate medicine dosage. Hope I helped with my answer. For further concerns or follow up questions do no hesitate to write again, I will be happy to answer you again. Kind regards, Dr. Ina