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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Glipizide Advisable Over Glyburide?

who makes this drug and why would i take it, I already take 1000 mg of metforminevery YYYY@YYYY , right now I am taking 1000 mg of metformin twice a day 27 units of lantus, and Glyburide 5mg one in the morning aznd two at supper last a1c aweek ago was 6 4mo ago 7 I don t understand why should I drop glyburide and take glipizide
Tue, 1 Aug 2017
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Endocrinologist 's  Response
Good day.
Noted your concern and glad that your Hba1c was 6% recently. Did you have any hypoglycemia episodes recently? Glyburide ( micronized glibenclamide) is much stronger than glipizide and since your recent Hba1c is good and ( if you had hypoglycemia) the doctor would probably want to change over to a less potent drug like Glipizide. From the available history, these are the possibilities for a suggested change over from Glyburide to glipizide.
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  Anonymous's Response
Anonymous's  Response
Glipizide has got less chances of hypoglycemia, as compared to glyburide.
and is safer for patients with mild kidney disease.

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Is Glipizide Advisable Over Glyburide?

Good day. Noted your concern and glad that your Hba1c was 6% recently. Did you have any hypoglycemia episodes recently? Glyburide ( micronized glibenclamide) is much stronger than glipizide and since your recent Hba1c is good and ( if you had hypoglycemia) the doctor would probably want to change over to a less potent drug like Glipizide. From the available history, these are the possibilities for a suggested change over from Glyburide to glipizide.