Hi and thanks for the query, Addisons disease is an endocrine disorder affecting the supra renal glands found above the kidneys. This pathology deserves particular and specific attention. Medication requires a complete review and tests in order to be able to adapt the prescription and doses. Effects might not be immediate since these are hormonal changes and require much time., Outcomes also differ from patient to patient. This therefore explains why you must consult a physician for proper follow up and management. I suggest you consult your primary care physician. Thanks and kind regards. Bain LE, MD.