Hello and welcome to HCM. Thank you for your query. Let me try to address each point from your query, so as to address all aspects and find the cause for your child s conditions. Starting with the urine analysis report which indicated some kind of infection and the culture report which reported normal uncontaminated urine. There are two possibilities for such a result: 1. A contaminated urine sample submitted for urine analysis, due to which an infection was reported; and a normal and accurate urine culture examination. In this case, there should be no urine infection 2. A normal and accurate urine analysis report and an inaccurate/incorrect urine culture report which did not detect the infection. This is unlikely, but can still happen. Thus, in my opinion, repeating both investigations, in a more experienced, and well-renowned laboratory would be preferable. Now coming to the rise in CRP. Did you check the CRP again? If yes, was there a further rise, a drop or approximately the same value? If you have not re-checked it, please do so. I would also like to provide you with some of the most common causes of a raised CRP, although it would be difficult to list them all. They are: -Heart diseases -Dental problems -Obesity -Arthritis -Viral diseases -Blood sugar abnormalities -Bacterial infections -Some medications As the fever is still present in your child, this is mostly indicative of some systemic illness or infection. Please re-visit your doctor, as a 10-day course of monocef should have cleared the infection (if present). There is also a possibility that your child is resistant to the particular antibiotic used (a culture and sensitivity examination will help rule this out). I hope I have succeeded in providing the information you were looking for. Please feel free to write back to me for any further clarifications. I would gladly help you. Best wishes.