Hello, sujathareddy4ever, Isolated elevation of Serum Amylase with all the rest of the liver tests being normal suggests that your pancreas may not be the cause of elevation. If you are not having any symptoms of abdominal pain, nausea, vomiting, fever etc. it is unlikely that you have acute pancreatitis which is an inflammation of the pancreas which produces insulin and also digestive enzymes. During the very phases of this condition, serum amylase will be elevated and subsequently serum lipase would also go up. Causes of pancreatitis, here in western culture, alcohol and gallstones predominate. Viral and other causes account for the rest. Amylase is also produced in the salivary gland. For example, if someone has Mumps their amylase levels could be elevated. There is a special test called fractionation of amylase that can show where it is coming from. Kidneys are also a source. I don t believe the fibroids have anything to do with this and finally a minor elevation could be perfectly normal for you. Wish you good health.