Hello and welcome, Thanks for your query. Assuming that the endoscopy or colonoscopy yielding results pointing to the diagnosis of IBS. A course of antibiotics (azithromycin) was advised for an infection. The most commonly used drugs to control a flare-up of IBS, are anti-spasmodics. You could have a discussion with your doctor about the possibility of using these group of drugs, it would greatly help. Also, please refer to the list of edibles that he could avoid (which can trigger a flare-up): -Fatty or fried foods -Foods that release sugars -Fizzy carbonated drinks/sodas -Caffeine -Spicy food -Popcorn -Raw vegetable, fruits, salads -Red meat -Dairy products -Tea -Hot (temperature) food I understand this condition can be frustrating, but if the proper precautionary measures are taken, it can be avoided. I hope I have helped in contributing in a small way at the least. Wishing you and your husband long healthy lives. Best wishes.