Yes, my wife has migraine headaches as a result of a whiplash several years ago. MRI showed minor damage to one of the vertebrae in her neck. If she sleeps in a position that puts strain on it, or with increased levels of stress, or combination of both, she gets the migraines. If she doesn t act on it right away, they become immobilizing. As a result, our doctor has prescribed Maxalt, which works for her. Her concern is what if any are the side effects of the Maxalt over time, or concurrent with taking it. It is a blessing to have such a med that you can rely on to pull you through those difficult times. Thank you for your consideration. Dwight Pincock.