Hi, Thanks for using HealthCareMagic. Alprazolam is very potent benzodiazepiene medicine. Long term effects as well as withrawal effects are alo much. In your case you are taking only 0.25 mg, that is good thing. It is not so high dose.So you can quit it somewhat easily. Two options: You can start a warm cup of milk before 15 minutes to bedtime and after one week you can take half tablet and after one eek of that you can totally stop. If you find difficulty with this approach and much sleep disturbance is there, you can consult doctor and start clonazepam 0.5 mg for sleep in stead of alprazolam.You can tapper off clonazepam easily. Hope I have answered your query. Regards, Dr.Chintan Solanki.