Thanks for putting up your query at HealthCareMagic. I am sorry that your daughter has Hailey–Hailey disease which is the other name of familial benign chronic pemphigus. It is characterized by outbreaks of rashes and blisters in the skin, usually in the folds of the skins, but also often over large areas of the body. The painful blisters break and sometimes become infected and raw, with new blisters forming over raw skin in a sometimes seemingly unending cycle of outbreaks. The cause of this disease is genetic insufficiency of an enzyme. Therefore if your daughter has already been correctly diagnosed to have the disease, it has already occurred and there is no way to prevent it. The only option is to keep it in control by using steroids and antifungals like Diflucan (fluconazole). Drugs such as antibiotics, antifungals, corticosteroids, dapsone, methotrexate, thalidomide, etretinate, cyclosporine and, most recently, intramuscular alefacept may control the disease but are ineffective for severe chronic or relapsing forms of the disease. Intracutaneous injections of botulinum toxin to inhibit perspiration may be of benefit. Some have found relief in laser resurfacing that burns off the top layer of the epidermis, allowing healthy non-affected skin to regrow in its place. I hope that helps. Feel free to revert back with further queries if any.