** 1. ESR reflects changes in plasma proteins, and is not diagnostic but suggestive of some ongoing pathology, and since Fibromyalgia is not an inflammatory condition thus one has to rule out other causes of high ESR [10 years] in body like: chronic infection, collagen vascular disease [any type of arthritis/ scleroderma] PS. Consult your Doctor regarding appropriate examination and relevant Investigations 2. Since you are a diagnosed case, and because there is no identifiable cause thus treatment is symptomatic, as a result both pharmacological and non pharmacological measures are used as adjuvant to get a good control of pain and extended symptom free period, such as: . Relaxation and stress management [stress is trigger response to fibromyalgia symptoms], thus yoga & Pranayama are helpful . Physiotherapy: wax massage, ultrasound/infra red technique to minimize pain. . Diet rich in omega 3 is considered helpful in alleviating fibromyalgia symptoms. . In Ayurveda we consider/manage the disease under Mans-Medo Gat Vaat , thus prescription medicines available are: chandraprabha vati, navak guggulu, trifla kwath,panchskar churan, navkarshik guggulu.