Hi, Thanks for writing in. Cisplatin is a chemotherapy agent and disintegrates into smaller metabolites within 30 minutes after it being injected. Medical literature says that the platinum from Cisplatin, but not Cisplatin itself, becomes bound to several plasma proteins, including albumin, transferrin, and gamma globulin. Three hours after an injection is started and about two hours after the end of a three-hour infusion, 90% of the plasma platinum is protein bound. This bound form is eliminated in 5 days from the time of injection. Chemo brain is a condition where there might be weakness and brain fog persisting after treatment. This is usually observed a cognitive change in the person with associated physical fatigue and weakness. No medications have been approved to treat chemo brain and patients might do well with psychological support and involving themselves in cognitive rehabilitation. Rarely medicines used to treat attention deficit disorders, Alzhiemers and sleep disorders might be of help. Please do not worry.