I have never had a cholesterol issue until I went to the hospital for a very minor stroke and although it was minor the cardiologist prescribed 40Mg Simvastin, once a day forever. I recently developed a sciatic nerve issue with the typical symptom of pain in the left buttox and down the left leg. I feel the diagnosis of sciatic nerve pain is correct but could their be some influence of the statin on muscle reaction that would inhibit my recovery period. Am taking 3 advil liquid gel twice a day for inflammation reduction and am getting some relief.