Overall joint stiffness and pain. Very difficult to move, can t sleep because of pain. Includes neck, shoulders, wrist, hands, lower back, hips and knees. Occasionally I also have numbness in my fingers and toes. Have been checked for RA and Lymes with negative results. Have done 2 rounds of short course Prednisone with relief but two days after I finish meds the pain comes back more severe.