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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Can Hypereosinophilic Syndrome Be Treated?

I have been diagnosed with idiopathic hypereosinophillic syndrome. My questions are. Doctor is not recommending treatment until there is symptoms of organ damage. How do I know when a organ is being affected or once there is damage to organ is it too late. Should I be doing as anything to get my eso percentage down.
Thanks
Wed, 25 Apr 2018
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Pathologist and Microbiologist,  's  Response
Hello and Welcome to ‘Ask A Doctor’ service.
I have reviewed your query and here is my advice.

Increased eosinophils that is hypereosinophilia has so many causes from reactive to malignant.

Most of the times, it is caused by allergic (asthma) or parasitic reasons, very rarely caused by chronic eosinphilic leukemia. So before starting the treatment, cause has to be identified.

if reactive causes are also ruled out then mutational analysis has to be done to rule out neoplastic causes like PDGFR and FLIPL1.

Organ damage by hyperesinophila is rare. So, my suggestion is please consult hematologist for correct diagnosis and proper treatment.

Hope I have answered your query. Let me know if I can assist you further.

Regards,
Dr. Siddartha
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How Can Hypereosinophilic Syndrome Be Treated?

Hello and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Increased eosinophils that is hypereosinophilia has so many causes from reactive to malignant. Most of the times, it is caused by allergic (asthma) or parasitic reasons, very rarely caused by chronic eosinphilic leukemia. So before starting the treatment, cause has to be identified. if reactive causes are also ruled out then mutational analysis has to be done to rule out neoplastic causes like PDGFR and FLIPL1. Organ damage by hyperesinophila is rare. So, my suggestion is please consult hematologist for correct diagnosis and proper treatment. Hope I have answered your query. Let me know if I can assist you further. Regards, Dr. Siddartha