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Dr. Andrew Rynne

Family Physician

Exp 50 years

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How can Depo Provera be removed from the blood stream?

Hi I was on the Depo Provera shot for a year. I first started in the summer of 2015. My last shot was on June 29th 2016. Then in Jaunary 31st, I went back on it because I had really bad period cramps. Is there a way I can cleanse it out of my system? Please let me know if there is anything I can try. Thank you!
Mon, 20 Mar 2017
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Infertility Specialist 's  Response
Hi, I think the depo shot remains active for 3 months. After that its effectgoes away. But when taken for long duration, it takes 6 months to one yearfor ovaries to regain its function. For period pain, you can use mefenamic acid. Discuss with your doctor regarding this.
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doctor1 MD

My periods are extreamly heavy to the point the going out or doing much of anything for that 5-7 is, a bit of a struggle so I chose to get onto Depo. I started using Depo in 2007 after having my child. I had no problems with it, and i completely stopped my periods within a month of recieving the shot. in 2011 I was told by the dr I was seeing that I would need to go off of depo for a year to allow my body a break. 3 months after stopping depo I found out this was not true. So of corse I started depo again. Only this time I began having problems with it. I got what I have heard called depo bleeding I would spot for 3-4 weeks at a time stop for a week maybe 2 and start again. the spotting was not bad sometimes its not even enough to leave anything in my uderwear. but when I would wipe I would have bloody residue. This continued for 7 months. because of this I stopped depo (that and my boyfriend is fixed) I went off of depo from 2012- july off 2014 a little over 2 years. my periods finally got back on normal (except the original problem of heavy bleeding). So i thought i would try depo again. I started it in july 2014. sense i have started it again i have depo bleeding again. at first it was for a full 3 months light spotting. months 4-6 would flux the 4rd month nothing no spotting, 5th month i spotted for 2 weeks then stopped for 2 weeks. Month 6 spotted all 4 weeks. i am now on month 7 i did not spot at all for the first week on the second week i had to have a colposcopy. I spotted 3 days after i got the colposcopy for a week. I figured this was normal. I stopped spotting for 2 days and last night i had heavy blood flow today as well. My questions are why did it work great the first time and now im having side effects on my 2nd and 3rd start. how can i get my periods to stop on depo. am i doing something wrong to make it have side effects. is there anything i can do?

doctor1 MD

Is there anyway to get depo provera our of my system. When I went to my annual Gyn appt my MD told me to have a period ( she gave me a medication to induce a period- I didn t take it and don t remember the name of it) then start my depo again. I m wanting to get pregnant in the next few months. My last dose of depo was Nov 2014

doctor1 MD

GOOD DAY - I AM ON DEPRO PREVERA FOR MANY YEARS NOW. 3 MONTHS AGO ALL I STARTED MY PERIOD AFTER NOT SEEING IT FOR MANY MANY YEARS. I AM CURRENTLY ON OVRAL 28 TOGETHER WITH THE INJECTION TO STOP BLEEDING. IF THIS CONTINUE CAN I STOP DEPRO PREV AND GO ON OVRAL 28. BUT I NOW IF YOU TAKE THE PILL AND START ON RED TABLETS YOU SEE YOUR PERIOD. IS IT ADVISABLE TO SKIP THE RED TABLETS EVERY MONTH NOT TO HAVE BLEEDING?