Get your Health question answered in 3 easy steps
A Doctor will be with you shortly
Ask a Doctor Now
182 Doctors are Online

How a medicine work on non insulin dependent diabetes mellitus [NIDDM]?

how a medicine work in niddm/
Asked On : Sat, 30 Oct 2010
Answers:  1 Views:  289
Report Abuse
Share on Facebook
Share on Twitter
Share on Google+
Question is related to
Diseases and Conditions
General & Family Physician 's  Response
Welcome to Health Care Magic Diabetic forum:

Metformin stimulates the insulin-induced component of glucose uptake into skeletal muscle and adipocytes in both diabetic individual (by pushing glucose from into skeletal muscles and fat tissue it decreases blood glucose levels).

Sulfonylurea binds to cells in Pancreas (called β-cells) and induces release of insulin into blood. Insulin ultimately decreases blood glucose.

TDZs (Actos and Avandia) has complex mechanism. They act on nuclear receptors called PPAR gamma. It results in alteration in the expression of genes involved in fat and glucose metabolism. Finally they increases insulin sensitivity, meaning Insulin action is increased on muscles and skeletal muscles
Good luck- Dr. Jagdish
Answered: Mon, 1 Nov 2010
I find this answer helpful

1 Doctor agrees with this answer

Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]


Loading Online Doctors....
© Ebix, Inc. All Rights Reserved.
All the information, content and live chat provided on the site is intended to be for informational purposes only, and not a substitute for professional or medical advice. You should always speak with your doctor before you follow anything that you read on this website. Any health question asked on this site will be visible to the people who browse this site. Hence, the user assumes the responsibility not to divulge any personally identifiable information in the question. Use of this site is subject to our Terms & Conditions
Already Rated.
Your rating:

Ask a Doctor